| Quantity: | |
|---|---|
Prucalopride Succinateis is a dihydrobenzofurancarboxamide compound that is a selective and high-affinity serotonin (5-HT4) receptor agonist with prokinetic activity in vitro and in vitro studies showing that prucalopric enhances the peristaltic reflex box in the gastrointestinal tract through 5-HT4 receptor activation.
1.Serotonin 5-HT4 Receptor Agonism: Serotonin is a neurotransmitter that plays various roles in the body, including the regulation of gastrointestinal motility. Prucalopride acts as a selective agonist of the serotonin 5-HT4 receptors in the colon. By activating these receptors, Prucalopride stimulates the release of acetylcholine, which enhances the contractions of the smooth muscles in the colon, leading to increased bowel movements.
2.Treatment of Chronic Idiopathic Constipation: Chronic idiopathic constipation (CIC) is a common gastrointestinal disorder characterized by infrequent and difficult bowel movements. It is considered "idiopathic" because the exact cause of the condition is not known. Prucalopride is indicated for the treatment of CIC in adults who have not responded adequately to other laxatives or treatments.
5.00kg/bag/drum, 5.00kg/bag, 2 bags/drum or according to customer’s requirements.
Prucalopride Succinateis is a dihydrobenzofurancarboxamide compound that is a selective and high-affinity serotonin (5-HT4) receptor agonist with prokinetic activity in vitro and in vitro studies showing that prucalopric enhances the peristaltic reflex box in the gastrointestinal tract through 5-HT4 receptor activation.
1.Serotonin 5-HT4 Receptor Agonism: Serotonin is a neurotransmitter that plays various roles in the body, including the regulation of gastrointestinal motility. Prucalopride acts as a selective agonist of the serotonin 5-HT4 receptors in the colon. By activating these receptors, Prucalopride stimulates the release of acetylcholine, which enhances the contractions of the smooth muscles in the colon, leading to increased bowel movements.
2.Treatment of Chronic Idiopathic Constipation: Chronic idiopathic constipation (CIC) is a common gastrointestinal disorder characterized by infrequent and difficult bowel movements. It is considered "idiopathic" because the exact cause of the condition is not known. Prucalopride is indicated for the treatment of CIC in adults who have not responded adequately to other laxatives or treatments.
5.00kg/bag/drum, 5.00kg/bag, 2 bags/drum or according to customer’s requirements.
