Pharmaceutical grade Ilaprazole API powder
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Pharmaceutical grade Ilaprazole API powder

CAS No.: 172152-36-2
Formula: C14H9Cl2NO4S
Type: Pharmaceutical API
Appearance: Powder
Certificate: GMP, COPP, WC, DMF
Shelf Life 2 years
Quality Standard CP, EP, JP, USP
Assay 98.0%-102.0%
Chemical Name :2-[(4-methoxy-3-methylpyridin-2-yl)methanesulfinyl]-5-(1H-pyrrol-1-yl)-1H-1,3-benzodiazole
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Product Description

Ilaprazole is a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. A weak base, ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.Ilaprazole has been investigated in Helicobacter Infections.

Function

Ilaprazole is a proton pump inhibitor. It is mainly used to treat duodenal ulcer, gastric ulcer, reflux Esophagitis and other syndromes, and can play an effective role in improving. The drug is mainly distributed in the acidic environment of Gastric mucosa parietal cells and can be transformed into active metabolites, which can inhibit gastric acid secretion by inhibiting active enzymes. Within 24 hours of medication, it has an inhibitory effect on basic and stimulated gastric acid secretion.

Package

5.00kg/bag/drum, 5.00kg/bag ,2 bags/drum or according to customer's requirements.


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Shandong Loncom Pharmaceutical Co., Ltd is founded in 2012, located in Qihe Economic Development Zone, Shandong Province, with a registered capital of 60 million yuan.

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