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Gefapixant Citrate (API, CAS No. 2310299-91-1) is a potent and orally bioavailable purinergic P2X3 receptor antagonist with high selectivity and nanomolar inhibitory activity toward human P2X3 receptor subtypes. As a novel active pharmaceutical ingredient targeting refractory or unexplained chronic cough (RCC/UCC), Gefapixant Citrate operates by blocking ATP-mediated P2X3 signaling pathways on sensory C-fibers, reducing hypersensitive cough reflexes and supporting improved patient outcomes in chronic cough research and therapeutic development.
This API is suited for pharmaceutical development, clinical formulation research, and mechanistic studies as part of prescription medicine R&D or advanced formulation pipelines. Its well-characterized receptor profile and clinical relevance make it an attractive component for companies engaged in respiratory disorder treatments and innovative cough therapeutics.
Function
Gefapixant citrate can be used to study chronic cough and knee Osteoarthritis.
Package
5.00kg/bag/drum, 5.00kg/bag ,2 bags/drum or according to customer’s requirements.
Gefapixant Citrate (API, CAS No. 2310299-91-1) is a potent and orally bioavailable purinergic P2X3 receptor antagonist with high selectivity and nanomolar inhibitory activity toward human P2X3 receptor subtypes. As a novel active pharmaceutical ingredient targeting refractory or unexplained chronic cough (RCC/UCC), Gefapixant Citrate operates by blocking ATP-mediated P2X3 signaling pathways on sensory C-fibers, reducing hypersensitive cough reflexes and supporting improved patient outcomes in chronic cough research and therapeutic development.
This API is suited for pharmaceutical development, clinical formulation research, and mechanistic studies as part of prescription medicine R&D or advanced formulation pipelines. Its well-characterized receptor profile and clinical relevance make it an attractive component for companies engaged in respiratory disorder treatments and innovative cough therapeutics.
Function
Gefapixant citrate can be used to study chronic cough and knee Osteoarthritis.
Package
5.00kg/bag/drum, 5.00kg/bag ,2 bags/drum or according to customer’s requirements.
